Mid-Atlantic BIOT Chapter Advisers
William J. Kelly, Faculty Adviser
Dr. William Kelly is a professor of Chemical Engineering at Villanova University. Prior to this, he worked as a biochemical engineer at Merck and Company for ten years. Dr. Kelly teaches and does research in the areas of upstream and downstream bioprocessing, primarily for Biopharmaceutical production. Dr. Kelly and his colleagues at Villanova recently won the ASEE Martin award for classroom innovation. Dr. Kelly’s research most recently has focused on optimization of microbioreactors and alternating tangential flow for perfusion cell culture applications. Dr. Kelly is currently looking at ways to improve growth of Tcells for improved CART therapies. Dr. Kelly is an alternate councilor on the BIOT EXCOMM and serves as BIOT liason to ESBES (European Symposium for Biochemical Engineering Sciences).
Kristopher (Kris) Barnthouse, Industry Adviser
Stijn Koshari, Industry Adviser
Throughout my career at GSK and graduate studies, I’ve had the opportunity to work on several projects related to biopharmaceutical research and development with collaborators in academia, industry, and national labs – particularly in the areas of downstream purification, formulation, and drug delivery – which have been published and presented at national conferences. Moreover, my experience in Downstream Process Development at GSK and my previous internship at Genentech’s South San Francisco campus have exposed me to a broad variety of aspects of the biopharmaceutical industry.
I believe my efficiency, love of problem-solving, and thirst for learning allow me to thrive in any position. In graduate school, I was involved in a wide range of student representation and engagement, often taking the responsibility of leading the group, for example as Vice President of Student Affairs in the UD Graduate Student Government. During my professional career, I've continued to mentor students, including as an industry advisor for senior design projects at the University of Pennsylvania and the Pennsylvania State University. Although I greatly enjoy teaching, which is reflected in my teaching fellowship at the University of Delaware and my hobby of teaching ballroom lessons to people of all ages, my internship experiences at Genentech and ExxonMobil inspired me to look for opportunities in the pharmaceutical industry. I chose to join GlaxoSmithKline (GSK) because of its authentic company culture and devotion to the patient.
Mid-Atlantic Student Officers
Brian Paul, President
Brian is a 4th year PhD student studying Chemical and Biomolecular Engineering at the University of Delaware. He grew up in Lake Forest, California and completed a double Bachelor’s in Chemical Engineering and Materials Science Engineering at University of California, Irvine. While at UCI, he was actively involved with AIChE and is excited to continue his professional development and service with ACS BIOT. Outside of the lab, he enjoys playing music, running, following politics, and volunteer math tutoring at local public schools.
Brian’s research focuses on studying and characterizing dense solid-like phases of proteins, specifically protein gels. Aggregation is a common occurrence in downstream bioprocessing and manufacturing, as well as pharmaceutical formulation, which can disrupt processes and lower production efficiency. On the other hand, precipitation can often be a useful and efficient method to purify a desired protein to high concentrations, and crystallization can be utilized to investigate protein structure via scattering or diffraction techniques. Determining the formation mechanism, mechanical properties, phase behavior, and structure of dense phases in common industrial proteins would allow for controlling aggregation in downstream bioprocessing. The goal of the project is to utilize a variety of characterization techniques, including bulk rheology, microrheology, small angle neutron scattering, and light scattering, to investigate the properties of these dense protein phases.
Roisin Donnelly, Webmaster
Roisin is a 4th year PhD candidate in Dr. Norman Wagner's group in the department of Biomedical and Chemical engineering at the University of Delaware. She is co-advised by Dr. Yun Liu at the NIST Center for Neutron Research, where she is currently based.
Roisin grew up mostly in Massachusetts but spent much of her life living also in Dublin, where she completed her undergraduate studies at Trinity College, obtaining a bachelor's degree in both biomedical engineering and also mathematics.
Justin Fisher, Recruiting & Communications Lead
Biochemical Engineering PhD candidate at Villanova University
Experienced Bioprocess Researcher with a demonstrated history of primary cell process development & CAR-T Cell process development. Skilled in Primary Cell Culture, Flow Cytometry and Bioprocess Data Analytics. I am a strong research professional, and currently a Ph.D Researcher in Biochemical Engineering at Villanova University where I focus on improving growth and efficacy of CAR-T cells.
Sara Su, Treasurer
Sara is a 4th year PhD candidate at the University of Pennsylvania.
Sara is multilingual, speaking Russian, Chinese, and English and has been described as a girl who is dedicated to her school work, passions and beliefs. At Penn, Sara spends most of her time manipulating intrinsically disordered proteins, aiming to achieve crosslinking effects. This can be leveraged to achieve her ultimate goal of creating synthetic cells.
University Institution Representatives
Christopher Domalewski, University of Delaware
Ivy, Pennsylvania University